relationships between serum luteinizing hormone level, endometrial thickness and body mass index in polycystic ovary syndrome patients with and without endometrial hyperplasia
نویسندگان
چکیده
objective: the endometrial hyperplasia measured by ultrasound in polycystic ovary syndrome (pcos) women is strongly related to pathologic endometrial thickness, but there is no consensus on the relation between serum luteinizing hormone (lh) and either of these factors: pathologic endometrial hyperplasia and body mass index (bmi). materials and methods: in this observational cross-sectional study, three hundred fifty infertile pcos women were involved in this research. an endometrial biopsy was taken by using a pipelle instrument, regardless of menstrual cycle’s day and all samples were reported by the same pathologist. basal serum lh level was compared between two subgroups (hyperplasia and non-hyperplasia). the intended population was divided into three groups according to bmi and basal serum lh, later on the comparison was made in three groups. chi-square test was applied to compare nominal variables between groups. mann-whitney u, and one way anova tests were used to compare means on the basis of the result of normality test. results: the frequency of endometrial hyperplasia was 2.6%. endometrial thickness in the patients with endometrial hyperplasia was significantly higher than that of a normal endometrium (10.78 ± 3.70 vs. 7.90 ± 2.86 respectively, p=0.020). there was no relation between endometrial hyperplasia and serum lh (p=0.600). the anova test showed serum lh levels were not the same among three bmi groups (p=0.007). post hoc test was also performed. it showed that the lh level in normal bmi group was significantly higher than those of other groups (p=0.005 and p=0.004), but there was no statistical difference between overweight and obese groups (p=0.8). we found no relationship between bmi and endometrial thickness in pcos patients (p=0.6). conclusion: sonographic endometrial stripe thickness is predictive for endometrial hyperplasia in pcos women. we could not find out any relationship between serum lh level and bmi with endometrial thickness in pcos patients. however, our study confirmed a diverse relationship between serum lh level and bmi in pcos patients.
منابع مشابه
P-99: Relationships between Serum Luteinizing Hormone Level, Endometrial Thickness and Body Mass Index in Polycystic Ovary Syndrome Patients with and without Endometrial Hyperplasia.
Background It is well documented that ulterasonographic endometrial hyperplasia in polycystic ovary syndrome (PCOS) women is strongly related to pathologic endometrial thickness, but there is no consensus on the relation between serum luteinizing hormone (LH) and either of these factors: pathologic endometrial hyperplasia and body mass index (BMI).��� MaterialsAndMethods An observational cross-...
متن کاملRelationships between Serum Luteinizing Hormone Level, Endometrial Thickness and Body Mass Index in Polycystic Ovary Syndrome Patients with and without Endometrial Hyperplasia
Objective The endometrial hyperplasia measured by ultrasound in polycystic ovary syndrome (PCOS) women is strongly related to pathologic endometrial thickness, but there is no consensus on the relation between serum luteinizing hormone (LH) and either of these factors: pathologic endometrial hyperplasia and body mass index (BMI). MaterialsAndMethods In this observational cross-sectional study, ...
متن کاملRelationships between Serum Luteinizing Hormone Level, Endometrial Thickness and Body Mass Index in Polycystic Ovary Syndrome Patients with and without Endometrial Hyperplasia
BACKGROUND The endometrial hyperplasia measured by ultrasound in polycystic ovary syndrome (PCOS) women is strongly related to pathologic endometrial thickness, but there is no consensus on the relation between serum luteinizing hormone (LH) and either of these factors: pathologic endometrial hyperplasia and body mass index (BMI). MATERIALS AND METHODS In this observational cross-sectional st...
متن کاملP-162: Body Mass Index and Polycystic Ovary Syndrome Women
Background: Polycystic ovarian syndrome (PCOS) is one of the most common endocrinology problems of infertile women. Since lifestyle modification and weight loss is the most effective treatment and associated with failure in many cases, this study evaluated the factors impact on weight loss of PCOS women. Materials and Methods: This cross- sectional study was conducted on 150 infertile women of ...
متن کاملSerum Adiponectin Level and Clinical, Metabolic, and Hormonal Markers in Patients with Polycystic Ovary Syndrome
متن کامل
The percentages of endometrial hyperplasia and endometrial cancer among polycystic ovary syndrome (PCOS) patients presenting with abnormal menstrual pattern.
OBJECTIVE Assess the occurrence of endometrial hyperplasia and endometrial cancer among PCOS patients having abnormal menstrual pattern. Endometrial thickness and other clinical characteristics associated with endometrial hyperplasia and endometrial cancer were also evaluated MATERIAL AND METHOD Women with PCOS and abnormal menstrual pattern were enrolled into this cross-sectional study. Endo...
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عنوان ژورنال:
international journal of fertility and sterilityجلد ۱۰، شماره ۱، صفحات ۳۶-۴۱
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